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Rey Parel

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Member of the Board of Directors in Several Medical Device Startups

experience

(Various)  
(Various), June 1985 to Present

I have more than 30 years of experience in the advanced technologies that enable the successful transition to manufacturing of microfluidics-based POC diagnostic devices, and over 20 years of direct involvement with biotechnology start-ups. This involvement encompassed the scale-up and commercialization of a wide array of leading-edge products, including PCR, qPCR, DNA sequencing, NGS, lab-on-a-chip, lab-on-a-disc, organ-on-a-chip, immonoassay, cell counting, sample prep, high density array, POC diagnostic and prognostic testing. These advanced technologies include cross-disciplinary expertise in microfluidics design, polymeric materials, surface activation, advanced replication methods, micro- and nano-molding technologies, advanced joining and encapsulation methods, sample prep methodologies from whole blood to saliva, multiplex designs, dense arrays, and nano biosensors, micopumps and valves, and the device optimization, commercialization and automation benchmarking that successfully launched these devices. I was involved in several industry firsts that highlighted his career. I was project leader for the first thin-wall Thermocycler Tubes, which enabled PCR as a core technology in DNA amplification and sequencing, and helped commercialize the first high-throughput PCR platform in the industry; lead the engineering team that produced the first plastic microfluidics lab-on-a-chip in the industry; lead the commercialization efforts in the first plastic microfluidics lab-on-a-disc; helped develop the smallest glucose meter in the world; helped develop the transition from silicon-glass to polymer-based process for the first PCR credit card size amplification chip with 2.8 million wells (30 micron diameter wells with beads). I helped design and develop a succession of novel POC diagnostic devices, which integrated sample prep, amplification, sequencing and assay, via a broad array of detection methods, including absorbance, laser, impedance, pH or temperature-based, and employing novel monolithic designs and dense array architecture.